Arsenal face their fiercest North London rivals, Tottenham, after a disappointing mid-week Champions League clash with Bayern Munich in Germany.
The Gunners versus Spurs tie climaxes a weekend that will also see Jose Mourinho come under the spotlight when his Chelsea team visit Stoke.
Mourinho faces a one-match stadium ban against same Mark Hughes’ side that eliminated his wards from the Capital One Cup last month.
Can the Gunners recover when Spurs visit the Emirates? Or will the absence of Mourinho affect the Blues at the Britannia?
Here are four exciting fixtures you shouldn’t miss this weekend.
- Manchester United vs. West Brom
Venue: Old Trafford
Kickoff: Saturday, 4pm
Head-to-head: Man Utd 5, Drawn 3, West Brom 2
Match facts
Wayne Rooney has scored seven goals and assisted four more in his last seven Barclays Premier League starts against West Bromwich Albion.
West Brom have lost just one of their last five league matches against Manchester United W2 D2 L1. Those two victories have come in their last two trips to Old Trafford.
Man Utd have kept more clean sheets than any other side in the BPL this term (seven).
- Stoke City vs. Chelsea
Venue: Britannia Stadium
Kickoff: Saturday, 6:30pm
Head-to-head: Stoke 1, Drawn 2, Chelsea 7
Match facts
Stoke City have won one of their last five Barclays Premier League matches at the Britannia Stadium (W1 D1 L3).
Prior to their recent League Cup penalty shoot-out defeat at Stoke, Chelsea had won 14 and lost just one of the previous 17 meetings in all competitions with them.
Chelsea have won just two of their last 10 away matches in all competitions (W2 D3 L5) and one of the draws ended in the shoot-out defeat by the Potters.
- Aston Villa vs. Man City
Venue: Villa Park
Kickoff: Sunday, 2:30pm
Head-to-head: Villa 2, Drawn 0, City 8
Match facts
Aston Villa have failed to score in five of the last seven Barclays Premier League meetings with Manchester City.
Man City have won seven and lost one of the last eight league encounters with Aston Villa.
Remi Garde will take charge of his first match as Aston Villa manager. He won his first league fixture in charge of Lyon (3-1 v Nice in August 2011).
- Arsenal vs. Tottenham
Venue: Emirates Stadium
Kickoff: Sunday, 5pm
Head-to-head: Arsenal 4, Drawn 2, Spurs 4
Match facts
Arsenal have won 13 and lost just two of their last 18 Barclays Premier League matches at Emirates Stadium, conceding just nine goals in that run.
Tottenham have won just one of their last 22 league trips to their north London rivals (W1 D8 L13).
The Gunners have scored 199 and conceded 97 goals in BPL London derbies on home soil. They also have earned 399 points from all London derbies.