For the third game in a row, Mikel Obi will miss Nigeria’s Africa Cup of Nations qualifier against South Africa.
The Super Eagles skipper who was exempted from the 23-man squad by coach Gernot Rohr, will also miss the friendly against Uganda, with Villarreal starlet Samuel Chukwueze getting his maiden invite.
In his absence, Al Nasr forward Ahmed Musa will carry on with captain duty.
Meanwhile, joining former U17 World Cup winner, Chukwueze for a potential debut is FC IfeanyiUbah defender Olamilekan Adeleye while Sporting Charleroi striker Victor Osimhen has been given a chance to replicate his form in Nigeria colours.
Surprisingly, Henry Onyekuru and Chidozie Awaziem have been dropped to the standby list which includes three Nigeria Professional Football League stars.
Nigeria sit top of Group E with nine points from four games while Stuart Baxter’s side are second in the group, trailing by two points.
The Super Eagles will look to get a victory over Bafana Bafana having lost the first leg 2-0 in Uyo.
The game is billed for November 17 at the FNB Stadium and three days later, the three-time African champions entertain the Cranes of Uganda at the Stephen Keshi Stadium, Asaba.
Full list:
Goalkeepers: Ikechukwu Ezenwa, Daniel Akpeyi, Francis Uzoho
Defenders: William Troost-Ekong, Leon Balogun, Kenneth Omeruo, Brian Idowu, Olamilekan Adeleye, Semi Ajayi, Jamilu Collins, Ola Aina.
Midfielders: John Ogu, Mikel Agu, Oghenekaro Etebo.
Forwards: Odion Ighalo, Ahmed Musa, Victor Osimhen, Alex Iwobi, Kelechi Iheanacho, Samuel Kalu, Isaac Success, Moses Simon, Samuel Chukwueze.